Sarcopenia and fragility fractures: molecular and clinical evidence of the bone-muscle interaction.
نویسندگان
چکیده
➤ Bone and muscle tissues are in close relationship, and the aging process is a factor involved in the loss of the functionality of both bones and muscles.➤ Sarcopenia and osteoporosis are linked from a biological and functional perspective and are related to an increased fracture risk in the elderly.➤ The increased fracture risk in sarcopenic and osteoporotic subjects is due to the decline of muscle mass and strength, the decrease in bone mineral density, and limited mobility.
منابع مشابه
Prevalence of Sarcopenia and Its Relationship with Sites of Fragility Fractures in Elderly Chinese Men and Women
OBJECTIVE Sarcopenia might be associated with bone fragility in elderly individuals. This study aimed to investigate the prevalence of sarcopenia and its association with fragility fracture sites in elderly Chinese patients. METHODS Patients (322 men and 435 women) aged 65-94 years and with a history of fragility fractures in the ankle, wrist, vertebrae or hip, and healthy men (n = 1263) and ...
متن کاملDairy in Adulthood: From Foods to Nutrient Interactions on Bone and Skeletal Muscle Health
The risk of fragility fractures exponentially increases with aging. Reduced mass and strength of both bone in osteoporosis and skeletal muscle in sarcopenia play a key role in the age-related incidence of fragility fractures. Undernutrition is often observed in the elderly, particularly in those subjects experiencing osteoporotic fractures, more likely as a cause than a consequence. Calcium (Ca...
متن کاملAssociation of New Coronavirus Disease With Fragility Hip and Lower Limb Fractures in Elderly Patients
The novel coronavirus-induced infection (COVID-19) was declared a pandemic by the World Health Organization onMarch 11, 2020. Iran is one of the countries with a high incidence of COVID-19 infection.Data on three patients with fragility hip fracture and COVID-19 infection were collected from one hospital located inBadrud, Isfahan, Iran, from March 1, 2010, to March 30, 2020. A...
متن کاملOsteoporosis: pathogenesis and clinical intervention.
Osteoporosis is a very common disorder and much has been learnt in recent years about the many pathogenic processes that contribute to bone loss and fragility. Drug treatments are now available to prevent bone loss and reduce fracture, and there are prospects for modifying some of the pathogenic processes themselves. In common with other structures, the tissues of the musculoskeletal system und...
متن کاملSarcopenia in Orthopedic Surgery.
Sarcopenia is a loss of skeletal muscle mass in the elderly that is an independent risk factor for falls, disability, postoperative complications, and mortality. Although its cause is not completely understood, sarcopenia generally results from a complex bone-muscle interaction in the setting of chronic disease and aging. Sarcopenia cannot be diagnosed by muscle mass alone. Diagnosis requires 2...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of bone and joint surgery. American volume
دوره 97 5 شماره
صفحات -
تاریخ انتشار 2015